These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Phenocopy of hepatocerebral dystrophy (Wilson-Konovalov disease)].
    Author: Makarova VA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1981; 81(11):1606-12. PubMed ID: 7324659.
    Abstract:
    For differentiating between hepatocerebral dystrophy (HCD) and its phenotypic analogues 70 patients with diseases of the subcortical ganglia and the cerebellum were examined. Some signs pathognostic of HCD (a transient drop of the ceruloplasmin level in the serum, a slight rise of the copper content in the hepatic tissue, subclinical signs of a hepatic pathology) may be encountered, though rarely, also in diseases of the subcortical ganglia and the cerebellum of other etiology. In obscure cases the diagnosis can be made clear only after carrying out a full complex of examinations, such as, revealing Kaiser-Fleischer rings, carrying out functional, radioisotopic and morphological examinations (by puncture biopsy) of the liver and determining the copper level in the latter. In patients with affections of the subcortical ganglia and the cerebellum, the liver is involved rather infrequently; the disturbances are of a subclinical character and can be classed with manifestation of drug disease, the extremes of which are fatty dystrophy and more frequently nonspecific changes.
    [Abstract] [Full Text] [Related] [New Search]