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  • Title: [Binding of 3H-diazepam by cerebral cortex synaptic membranes in the rat during conditioned reflex elaboration].
    Author: Korotkov KO, Zhulin VV, Kruglikov RI.
    Journal: Biull Eksp Biol Med; 1981 Dec; 92(12):695-6. PubMed ID: 7326418.
    Abstract:
    In-vitro experiments were made to compare specific binding of 3H-diazepam with synaptic membranes obtained from the large hemispheres of rats trained the defense conditioned reflex to that in rats exposed to non-combined stimuli (active control). Within the concentration range of 0.37 nM-30 nM, specific binding of 3H-diazepam with the synaptic membranes obtained from the brain of active control animals was considerably higher than that with the synaptic membranes obtained from the trained animals brain.
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