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  • Title: [Induced leukemias. Cytogenetical and cytological aspects. Comparison with primitive leukemias (author's transl)].
    Author: Berger R, Bernheim A, Daniel MT, Valensi F, Flandrin G.
    Journal: Nouv Rev Fr Hematol (1978); 1981; 23(5):275-84. PubMed ID: 7329804.
    Abstract:
    25 presumably induced leukemias, either following treatment (lymphoma, polycythemia vera, essential thrombocythemia, cancers) or after exposure to oncogenic agents have been studied cytogenetically and cytologically. Complex chromosomal abnormalities were associated with a difficult cytological classification. Complete monosomy 7 with presence of micromegacaryocytes and macroplatelets was observed in 7 cases. The findings observed in induced leukemias were compared with those found in "primitive" leukemias showing the same chromosomal patterns. The same relationships between cytology and cytogenetics have been observed.
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