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  • Title: Haemodynamics of isolated versus dialytic ultrafiltration in the unanaesthetised, non-uraemic dog.
    Author: Daugirdas JT, Chen WT, Ing TS, Vestal RE, Popli S, Hano JE, Jacobs HK.
    Journal: Proc Eur Dial Transplant Assoc; 1981; 18():139-45. PubMed ID: 7329961.
    Abstract:
    Ten alert, non-uraemic, splenectomised dogs were subjected to isolated ultrafiltration until mean arterial pressure decreased to less than 80mmHg. On a separate occasion, in the same dogs, ultrafiltration was performed in the course of haemodialysis. Whether or not dialysate was circulated, ultrafiltration resulted in marked increases in total peripheral vascular resistance, and large increases in plasma concentrations of vasoactive hormones, including norepinephrine. Our results suggest that, in the non-uraemic dog, the haemodynamic responses to ultrafiltration during dialysis and to isolated ultrafiltration are similar.
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