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  • Title: Intravascular neutrophilic granulocyte kinetics in horses.
    Author: Carakostas MC, Moore WE, Smith JE.
    Journal: Am J Vet Res; 1981 Apr; 42(4):623-5. PubMed ID: 7332122.
    Abstract:
    Intravascular granulocyte kinetics in 4 healthy horses were determined with chromium-51 as the cell label. The disappearance rate of labeled granulocytes was an exponential function. Mean total blood granulocyte pool (+/- 1 SD) was 5.65 +/- 1.514 X 10(8) granulocytes/kg of body weight, of which 2.71 +/- 0.715 X 10(8) granulocytes/kg were circulating and 2.94 +/- 0.876 X 10(8) granulocytes/kg were marginated along blood vessel walls. The mean disappearance half-life (T1/2) was 10.5 +/- 1.33 hours and the mean granulocyte turnover rate was 8.84 +/- 1.495 X 10(8) granulocytes/kg/day. A granulokinetic trial performed on a horse recovering from a recent infection revealed increases in all granulokinetic measurements.
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