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  • Title: [Breast cancer and use of antihypertensive drugs and oral contraceptives: results of a case-control study (author's transl)].
    Author: Clavel F, Lê M, Laplanche A.
    Journal: Bull Cancer; 1981; 68(5):449-55. PubMed ID: 7332791.
    Abstract:
    A case control study in breast cancer was conducted in France between 1976 and 1980. 1 031 patients with histologically confirmed cancer of the breast were entered into the study. Each was matched on age (+/- 5 years) to two controls hospitalized in the same clinic for a benign disease. We have specially studied the anti-hypertensive drugs, and the oral contraceptives. We found no difference between cancer patients and controls concerning their consumption of anti-hypertensive drugs, whether containing reserpine or not, and their consumption of oral contraceptives. However, there is a relation between the use of oral contraceptives and the age, family status and social class of women. After adjustment on these factors, we found a 1.62 relative risk of developing a cancer of the breast among the women using oral contraceptives (p less than 0.02).
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