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  • Title: Primary sleep apnoea syndrome.
    Author: Chokroverty S, Sharp JT.
    Journal: J Neurol Neurosurg Psychiatry; 1981 Nov; 44(11):970-82. PubMed ID: 7334397.
    Abstract:
    Polygraphic study in 18 men with the sleep apnoea syndrome showed central, upper airway obstructive, and mixed apnoeas. Fifty per cent of the total apnoea time was central, 33% was obstructive, and 17% was mixed. Apnoeic episodes were accompanied by oxygen desaturation, relative bradycardia and hypotonia of orofacial muscles innervated by ponto-medullary neurons. During regular breathing these muscles revealed tonic and phasic inspiratory EMG activities. The data suggest that the primary sleep apnoea syndrome results from a dysfunction of the central control of breathing.
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