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  • Title: Glomerular podocyte cell junctions in nephrotic syndrome. II. Freeze-fracture studies in human nephrotic syndrome.
    Author: Kühn K, Baldamus CA, Brandis M, Reale E.
    Journal: J Submicrosc Cytol; 1981 Jul; 13(3):413-21. PubMed ID: 7334545.
    Abstract:
    In six patients with nephrotic syndrome and in two control subjects freeze-fracture studies of isolated glomeruli obtained by needle biopsies were performed. In the nephrotic patients replicas of freeze-fractured podocytes showed an increased number of cell junctions. These were represented by incomplete occluding junctions and communicating junctions (gap junctions). There was morphologically a similarity between the glomerular podocyte cell junctions in human and experimental nephrotic syndrome (Kühn et al., 1981).
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