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  • Title: [Neurochemical data concerning glial tumors. Contribution of the estimation of the G.F.A. protein to the diagnosis and prognosis of gliomas (author's transl)].
    Author: Jacque C, Baumann N.
    Journal: Neurochirurgie; 1981; 27(5):255-6. PubMed ID: 7335129.
    Abstract:
    The Glial Fibrillary Acidic (G.F.A.) protein is a specific component of the gliofilaments present in the astrocytes. Its immunochemical determination on tumor fragments obtained at surgery has permitted to draw clinico-biochemical correlations between the G.F.A. content of a glioma and its histological grade. The more a glioma is dedifferentiated, the lower is its content of G.F.A. This determination is a biochemical index of dedifferentiation. However, its pronostic value is not established yet.
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