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  • Title: An extremely attenuated, live measles virus vaccine (CAM-EX). Persistence of low titer-antibody in institutionalized children with psychomotor retardation after vaccination.
    Author: Ueda K, Hashiguchi K, Nakashima F, Ueda S, Takahashi M.
    Journal: Biken J; 1981 Sep; 24(3):119-22. PubMed ID: 7337678.
    Abstract:
    Fifty children with psychomotor retardation, who had no detectable measles hemagglutination-inhibition (HI) antibody, were vaccinated with an extremely attenuated, live measles virus vaccine (CAM-EX). Only 10% of the children had fever after vaccination. No other symptoms were observed. Forty of 44 vaccinated children showed increase in HI antibody titers of 2(3) or more, with a geometric mean titer of 2(4.2). A five-year follow-up study revealed that the initially low-titer antibodies persisted well under conditions without a booster response due to natural measles.
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