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  • Title: Pregnancy diagnosis in Macaca fascicularis. Hemagglutination inhibition test for urinary chorionic gonadotropin and implantation bleeding.
    Author: Boot R, Huis in 't Veld LG.
    Journal: J Med Primatol; 1981; 10(2-3):141-8. PubMed ID: 7338888.
    Abstract:
    The Subhuman Primate Pregnancy Tube Test (SHPT test) was useful for early pregnancy diagnosis in cynomolgus monkeys (Macaca fascicularis). Test results were correct in 86.5% of series of four successive urine samples. SHPT test results were not confirmed in 13.5% of series, comprising two (false) negative series in pregnant animals and 13 (false) positive series in nonpregnant animals. In ten of 13 false-positive series, a positive-negative sequence was observed in successive test results, presumably due to a decline in chorionic gonadotropin levels. In all animals with a false-positive SHPT test, early embryonic mortality was most probable, since all showed normal cycling activity immediately afterwards. Postmating bleeding records were not reliable for pregnancy diagnosis. A practical approach for the use of the SHPT test in the individual breeding of monkeys is given.
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