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  • Title: Effect of dietary vitamin E and selenium on the phytohaemagglutinin response of pig lymphocytes.
    Author: Larsen HJ, Tollersrud S.
    Journal: Res Vet Sci; 1981 Nov; 31(3):301-5. PubMed ID: 7342224.
    Abstract:
    A whole-blood lymphocyte transformation test was used to study the effect of dietary vitamin E and selenium supplementation on the phytohaemagglutinin (PHA) response of peripheral pig lymphocytes. Six groups of pigs were given various amounts of alpha-tocopherol and, or, sodium selenite for a period of 12 weeks. At the end of the experiment all groups given additional vitamin E and, or, selenium showed increased PHA-response. Vitamin E supplementation enhanced the mitogen response at all tested levels of selenium addition. The activities of the different cell types involved in increased immune response due to vitamin E and selenium supplementation are discussed.
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