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  • Title: Half-life of 13,14-dihydro-15-keto prostaglandin f2 alpha in peripheral plasma of the pig.
    Author: Martin KA, Liptrap RM.
    Journal: Res Vet Sci; 1981 Nov; 31(3):387-9. PubMed ID: 7342231.
    Abstract:
    The metabolite of prostaglandin F2 alpha (PGF2 alpha ) namely 13,14-dihydro-15-keto-prostaglandin F2 alpha (PGFM), was administered as an intravenous bolus injection into five adult pigs. Concentrations of PGFM in blood collected periodically after injection indicated a biexponential decline suggesting a rapid distribution to the extracellular fluid and a slower elimination by metabolism. A mean half-life value of 14.97 +/- 1.33 (SD) minutes was calculated for the second component of the decline in PGFM concentration.
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