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  • Title: [Variations in human parasitic diseases: malaria and schistosomiasis (author's transl)].
    Author: Garin JP.
    Journal: Bull Soc Pathol Exot Filiales; 1981; 74(6):739-49. PubMed ID: 7343140.
    Abstract:
    Until now, not any human vaccine against parasites can't be prepared. However, experimental researches are more and more numerous, with two major aims: Malaria and Schistosomiasis. Three vaccines are considered in Malaria: --sporozoite-vaccine, --merozoite-vaccine, --gametocyte-vaccine. Important advances were realized after the control of new techniques: --in vitro cultivation of malaria parasites, --production of monoclonal antibodies, --industrial breeding of anopheles. But the applications in men still remain a remote object. The vaccines against schistosomiasis can be killed vaccines or live vaccines; the use of radio-vaccines is full of promise. The difficulties of vaccination against protozoal or helminthic parasites are due in part to the misappreciation of real defensive means in the parasited host. A serious progress would be to devise artificial systems drawing near of physiological phenomenons.
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