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  • Title: [Must renal biopsy be still performed in "lipoid nephrosis"? (author's transl)].
    Author: Del Gado R, Polito C, Strano CG, Di Toro R.
    Journal: Pediatr Med Chir; 1981; 3(5):399-401. PubMed ID: 7343933.
    Abstract:
    In 52 out of 272 children with one of the following diseases: nephrotic or nephritic syndrome, persistent humaturia and/or proteinuria, renal biopsy was performed on the basis of commonly accepted indications. 18 biopsies were from patients with a clinical picture of lipoid nephrosis and clinical course of "non responders" or "frequent relapsers" types. All of them showed the histologic pattern of minimal changes and had a value of Y index according to ISKCD greater than 0,85. Moreover all patients with minimal changes nephrotic syndrome had a Y index greater than 0.85. If these observations will be confirmed renal biopsy would not later be indicated in children with "lipoid nephrosis".
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