These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Substrate concentration changes during pregnancy in the conscious rat.
    Author: Gilbert M, Pégorier JP.
    Journal: J Dev Physiol; 1981 Dec; 3(6):343-54. PubMed ID: 7347349.
    Abstract:
    Weight gain, food intake and blood metabolite concentrations were investigated in conscious pregnant and non-pregnant rats. A silastic catheter was inserted under light diethyl ether anaesthesia into the carotid artery. Surgery did not significantly affect the weight gain or food intake in pregnant and non-pregnant rats compared with non-operated females. Blood glucose concentration, which was constant during the last half of pregnancy, was 1.4-fold lower than in non-pregnant rats. Blood lactate and pyruvate concentrations were similar in non-pregnant and in pregnant animals until 16.5 days of gestation. Then blood lactate concentration was increased by 50% between 16.5 days of gestation and term, whereas in the same period of pregnancy, blood pyruvate concentration was unchanged. Blood alanine concentration was increased by 150% from 13.5 days of gestation to term. Plasma non-esterified fatty acids concentration increased progressively during the second half of pregnancy to reach values 2-fold higher than in non-pregnant rats. Blood ketone bodies concentrations were unchanged during pregnancy and similar to those observed in non-pregnant animals.
    [Abstract] [Full Text] [Related] [New Search]