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  • Title: Urinary tract infections in children: effect of short course antibiotic therapy on recurrence rate in children with previous infections.
    Author: Fennell RS, Luengnaruemitchai M, Iravani A, Garin EH, Walker RD, Richard GA.
    Journal: Clin Pediatr (Phila); 1980 Feb; 19(2):121-4. PubMed ID: 7351102.
    Abstract:
    Eighty-five girls, ages 3-16, with a past history of recurrent urinary tract infections were treated for 10 days with either trimethoprim/sulfamethoxazole, ampicillin or cephalexin. Patients with normal roentgenograms as well as those with reflux and cortical scarring were included. In the 12 weeks following completion of treatment, a significantly lower recurrence rate was noted in children who received trimethoprim/sulfamethoxazole. There was no difference in the recurrence rate whether or not radiographic abnormalities were present. No serious side effects were noted with any drug regimen.
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