These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Red cell sodium and potassium in hemorrhagic shock measured by lithium substitution analysis.
    Author: Day B, Friedman SM.
    Journal: J Trauma; 1980 Jan; 20(1):52-4. PubMed ID: 7351678.
    Abstract:
    A new method of measuring intracellular Na and K using Li substitution analysis was applied to a study of red cell Na changes in hemorrhagic shock. Using a rat hemorrhagic shock model, significant changes in red cell Na were found after 2 hours. Red cell Na in shocked animals was significantly higher than in control animals (p less than 0.025). A small decrease in red cell K occurred. There was no intracellular shift of Li. In addition, a fall in plasma Na and a rise in plasma K occurred with progressive shock. In a 2-hour period following retransfusion there was no significant change in cell Na or K, but the plasma Na and K returned toward preshock levels. These results confirm a prolonged and significant impairment of red cell membrane function in shock and suggest that impaired Na-K pump function may be responsible for the changes.
    [Abstract] [Full Text] [Related] [New Search]