These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Identification of a decarboxylation product of retinoic acid.
    Author: Rockley NL, Halley BA, Nelson EC.
    Journal: Biochim Biophys Acta; 1980 Feb 07; 627(3):270-5. PubMed ID: 7353057.
    Abstract:
    The oxidative decarboxylation of retinoic acid was investigated utilizing a model system consisting of all-trans-retinoic acid, H2O2 and horseradish peroxidase. The decarboxylation products were purified by high-performance liquid chromatography on bonded, octadecylsilane columns. Based on mass spectral, nuclear magnetic resonance, ultraviolet and Fourier transform infrared analyses, the major decarboxylation product was identified as a 4-oxo-C19 aldehyde with a hydroxyl group on the side chain at C9, specifically 8-(2,6,6-trimethyl-3-oxocyclohex-1-enyl)2,6-dimethyl-6-hydroxyoctatrienal.
    [Abstract] [Full Text] [Related] [New Search]