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  • Title: Cytology and colposcopy in the diagnosis and management of outpatients with cervical intraepithelial neoplasia.
    Author: Allahverdian V, Valaitis J, Kalis O, Pearlman S.
    Journal: J Reprod Med; 1980 Jan; 24(1):1-4. PubMed ID: 7359496.
    Abstract:
    One hundred consecutive outpatients seen in the colposcopy clinic of a private hospital had one or more Papanicolaou smears that suggested cervical atypia, dysplasia or carcinoma in situ. Of these 100 patients, 7% underwent a diagnostic cervical cone biopsy; 11% more had therapeutic conization. The accuracy of colposcopic examination with directed cervical biopsy within one level (under or over) of histologic findings was 88%; the cytologic accuracy within one level of histologic findings was 83%. The study showed that patients with cervical atypia at cytologic examination had dysplasia and carcinoma in situ at subsequent colposcopic cervical examination with directed biopsy.
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