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  • Title: Evaluation of methods used to estimate inhaled dose of carbon monoxide.
    Author: Rees PJ, Chilvers C, Clark TJ.
    Journal: Thorax; 1980 Jan; 35(1):47-51. PubMed ID: 7361284.
    Abstract:
    We have compared estimation of alveolar carbon monoxide measured either as end-expired or mixed-expired carbon monoxide tension with two spectrophotometric estimations of venous blood carboxyhaemoglobin (COHb). Estimation of mixed-expired carbon monoxide proved more convenient for patients than the end-expired method, and this estimation of carbon monoxide exposure discriminated between non-smokers and smokers as well as measurements of COHb. The technique is bloodless, economical, and simple to perform. It should prove a valuable method for validating reported smoking habits of people attending smoking advisory centres and for epidemiological surveys of smoking.
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