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  • Title: Coagulation properties of fresh-frozin canine plasma during prolonged storage.
    Author: Greene CE, Beck BB.
    Journal: Am J Vet Res; 1980 Jan; 41(1):147-50. PubMed ID: 7362120.
    Abstract:
    Coagulation properties of fresh platelet-poor canine plasma from 20 dogs were examined before freezing and after storage at intervals of up to 1 year. Prothrombin time and factor V activity did not change in frozen plasma when compared with data obtained after plasma was stored 1 week. When compared with that of fresh plasma, activated partial thromboplastin time shortened and factor VIII activity decreased after freezing and thawing of fresh plasma after 1 week, activated partial thromboplastin time in fresh-frozen plasma gradually shortened during the year of storage. Factor viii activity increased in the first 4 months of storage, but gradually decreased by 1 year.
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