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  • Title: [Malignant histiocytosis with cutaneous involvement: enzymecytochemical and immunocytological studies (author's transl)].
    Author: Büchner SA, Rufli T.
    Journal: Dtsch Med Wochenschr; 1980 Mar 14; 105(11):373-7. PubMed ID: 7363775.
    Abstract:
    Malignant histiocytosis with cutaneous involvement occurred in a 27-year-old man. There were generalized weakness, abdominal pain, lymphadenopathy, fever and firm, papulonodular cutaneous infiltrations. The tumour cells were identified as malignant histiocytes by specially adapted enzyme-cytochemical and immunocytological methods on cryostat sections and single-cell suspension from the cutaneous infiltrates. The malignant histiocytes are characterized by diffuse activity of esterases and acid phosphatase. In addition, tests in single-cell suspension make it possible to differentiate the cells further according to cytomorphological and enzyme-cytochemical criteria.
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