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  • Title: Tranexamic acid and gastric fibrinolysis in the rat.
    Author: Stenberg B, Risberg B, Peterson HI.
    Journal: Thromb Haemost; 1980 Feb 29; 42(5):1425-8. PubMed ID: 7368148.
    Abstract:
    An optimal inhibition of tissue fibrinolysis, studied by a histochemical fibrin slide technique in the rat stomach, was obtained by administration of tranexamic acid in a dose of 60 mg/100 g body weight. A significant fibrinolysis inhibition was found within 5 min, when tranexamic acid in this dose was given either intravenously or intragastrically. A prolonged duration of fibrinolysis inhibition was observed after intragastric administration. After 4 hr no inhibitory effect of tranexamic acid could be recorded, irrespective of the route of administration.
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