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  • Title: Childhood hyperthyroidism. Results of treatment.
    Author: Mäenpää J, Kuusi A.
    Journal: Acta Paediatr Scand; 1980 Mar; 69(2):137-42. PubMed ID: 7368921.
    Abstract:
    40 hyperthyroid children were followed for 0.2--12 (mean 4.5) years. The treatment was antithyroid drugs in 20, subtotal thyroidectomy after a drug trial in 18 and primary thyroidectomy in 2 patients. 4 patients who relapsed (3 after surgery and 1 after a drug trial) were given radioiodide. 11 of the surgically treated glands were nodular. At the follow-up study 24 patients were euthyroid, 7 were on thyroxine therapy and in 5 others hypothyroidism was discovered. 2 subjects were still on antithyroid drugs and 2 relapsed. In 5 euthyroid patients the TRH test revealed a low thyroid reserve. In 28 of 34 subjects examined circulating antibodies to thyroid microsomes were present in high titres. Evidently, regular follow-up is needed because of the high risk of hypothyroidism.
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