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  • Title: Non-competitive inhibition of bradykinin, acetylcholine and histamine on guinea-pig ileum with streptomycin and vitamin K3.
    Author: Altinkurt O, Kanzik I.
    Journal: Arzneimittelforschung; 1980; 30(1):41-4. PubMed ID: 7370072.
    Abstract:
    Streptomycin and vitamin K3 were studied on the guinea-pig ileum for their effects on the cumulative dose-response curves of bradykinin, acetylcholine and histamine. Streptomycin and vitamin K3 antagonized each of these agonists non-competitively. The comparison of the non-competitive affinities of the antagonists indicate that all of these agonists antagonized by a common mechanism.
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