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  • Title: [Dopamine and renal homeostatic control of osmolarity and extracellular fluid volume in initial conditions of hydro-saline depletion and retention. II. Relationship between the renal functional parameters].
    Author: Agnoli GC, Cacciari M, Garutti C, Lenzi P.
    Journal: Boll Soc Ital Biol Sper; 1980 Feb 15; 56(3):280-6. PubMed ID: 7370121.
    Abstract:
    In hydro-saline depletion dopamine (DA) infusion (0,1 microgram.kg-1.min-1) elicits different renal effects than it does in hydro-saline retention. It is suggested that in hydro-saline depletion DA activates, besides vasal DA receptors, also vasal and tubular adrenergic receptors. Such adrenergic activation, either direct or presynaptically mediated, can account for both the decrease in the hyperemic response and the increase in the anisosmotic sodium reabsorption.
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