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  • Title: [Polyploidization mechanisms of the cardiac myocytes in the mouse].
    Author: Uryvaeva IV, Aref'rva AM, Brodskiĭ VIa.
    Journal: Biull Eksp Biol Med; 1980 Feb; 89(2):219-22. PubMed ID: 7370428.
    Abstract:
    Ventricular cardiomyocytes of 5-6 day-old mice are mostly polyploid. At this time 60% of the cardiomyocytes become binuclear and another 10% mononuclear polyploids. The binuclear cardiomyocytes emerge as a result of acytokinetic mitosis, while mononuclear tetraploids as a result of the cessation of the mitosis at the initial stages.
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