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  • Title: Is there a blood-brain relationship for saturated fatty acids during development?
    Author: Bourre JM, Gozlan-Devillierre N, Daudu O, Baumann N.
    Journal: Biol Neonate; 1978; 34(3-4):182-6. PubMed ID: 737240.
    Abstract:
    Transport of subcutaneously injected [1-14C]-stearic acid through the blood-brain barrier is compared with endogenous biosynthesis (within the brain) during postnatal brain development in mice. The uptake is very important during glial cell multiplication and myelination; endogenous microsomal synthesis is most active during myelination, soluble de novo mechanism is prominent during cell multiplication (mitochondrial systems are not directly related to these events). A parallel is drawn between myelin fatty acids, microsomal synthesis and uptake from the blood.
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