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  • Title: Clinical significance of synovial fluid total hemolytic complement activity.
    Author: Kim HJ, McCarty DJ, Kozin F, Koethe S.
    Journal: J Rheumatol; 1980; 7(2):143-52. PubMed ID: 7373616.
    Abstract:
    Total hemolytic complement (CH50) was measured in 174 synovial fluids (SF) to determine its diagnostic and and prognostic value. SF CH50 was reduced relative to serum CH50 in 61% of patients with rheumatoid arthritis and 60% of patients with crystal-induced arthritis. There was no correlation of SF CH50 levels with disease duration, SF leukocyte count, presence of IgM rheumatoid factor, or radiologic evidence of erosions.
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