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  • Title: Lipopolysaccharides of R mutants isolated from Vibria cholerae.
    Author: Hisatsune K, Kondo S.
    Journal: Biochem J; 1980 Jan 01; 185(1):77-81. PubMed ID: 7378055.
    Abstract:
    The chemical and serological properties of lipopolysaccharides isolated from the S form and from the R form of cholera vibrios were compared. It was found that the S-R mutation of cholera vibrios involves total elimination of the two component amino sugars of S-form lipopolysaccharides, i.e. quinovosamine and perosamine. This elimination resulted in the loss of O-specificity of S-form lipopolysaccharides and concomitant appearance of strong serological cross-reactivity, in the passive-haemolysis-inhibition test, among R-form lipopolysaccharides regardless of the serotypes (Inaba and Ogawa) of their S parent strains.
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