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  • Title: Size reduction of a prolactin secreting adenoma during long-term treatment with the dopamine agonist lisuride.
    Author: Chiodini PG, Liuzzi A, Verde G, Cozzi R, Silvestrini F, Marsili MT, Horowski R, Passerini F, Luccarelli G, Borghi PG.
    Journal: Clin Endocrinol (Oxf); 1980 Jan; 12(1):47-51. PubMed ID: 7379313.
    Abstract:
    A 38-year-old amenorrhoeic woman suffering from a prolactin (PRL) secreting adenoma, which had suprasellar extension as shown by caroe agonist (lisuride). PRL levels were lowered and after 1 year of treatment CAT showed a marked reduction of the tumour size. After 2 years of treatment menstruation returned and CAT demonstrated a further reduction of the adenomatous tissue. This study supports the suggestion that dopamine agonists possess an anti-proliferative effect on tumoural lactotrophic cells of humans.
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