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  • Title: Orally active cephalosporins and penicillins.
    Author: Böhme EH, Bambury RE, Baumann RJ, Erickson RC, Harrison BL, Hoffman PF, McCarty FJ, Schnettler RA, Vaal MJ, Wenstrup DL.
    Journal: J Med Chem; 1980 Apr; 23(4):405-12. PubMed ID: 7381838.
    Abstract:
    A number of orally active cephalosporins and penicillins with interesting biological activity were synthesized. Two of these, 7-[[[3,4-(methylenedioxy)phenyl]glycyl]amino]deacetoxycephalosporanic acid and 7-[[2-(2,3-dihydro-5-benzofuranyl)glycyl]amino]deacetoxycephalosporanic acid were considerably more active than cephalexin both in vitro and in vivo against staphylococcal and streptococcal infections.
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