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  • Title: Time-synchronized activation of lipolysis and fatty acids reacylation by bradykinin and angiotensin II in the perfused rabbit kidney.
    Author: Raz A, Schwartzman M.
    Journal: Adv Prostaglandin Thromboxane Res; 1980; 6():255-8. PubMed ID: 7386267.
    Abstract:
    BK and AII administered to the isolated perfused rabbit kidney activate two sequential enzymatic processes: 1) a selective release of the PG precursor, AA with concomitant, partial conversion of arachidonate to PGE2. 2) Activation of a reacylation process which leads to decreased release of all fatty acids in the perfusate. There is a lag time of approximately 1 min between initial activation of the arachidonate-specific deacylation reaction that is coupled to PG generation, and subsequent activation of the reacylation process.
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