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  • Title: Familial retinoblastoma: segregation of chromosome 13 in four families.
    Author: Knight LA, Gardner HA, Gallie BL.
    Journal: Am J Hum Genet; 1980 Mar; 32(2):194-201. PubMed ID: 7386455.
    Abstract:
    Fluorescent markers on chromosome 13 have been used to study familial retinoblastoma. One family showed concordant segregation of a particular chromosome 13 and retinoblastoma from the affected parent to the affected children. In three other families, segregation was discordant. Meiotic crossing over with recombination is proposed as the explanation.
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