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  • Title: Cryosurgical treatment of cervical intraepithelial neoplasia.
    Author: Ostergard DR.
    Journal: Obstet Gynecol; 1980 Aug; 56(2):231-3. PubMed ID: 7393513.
    Abstract:
    This report describes 354 patients treated with cryosurgery for cervical intraepithelial neoplasia (CIN) over an 8-year period. Colposcopic criteria were used to select treatable patients and to perform colposcopically directed biopsies. Treatment failures occurred in 6.2% of 298 patients treated for CIN I and II lesions. Of patients treated for carcinoma in situ, 39% demonstrated persistence of this lesion. Based on this clinical experience, cryosurgery is no longer acceptable for the treatment of severe dysplasia or cervical carcinoma in situ.
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