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  • Title: [New aspects in the treatment of cardiac insufficiency].
    Author: Burkart F.
    Journal: Schweiz Med Wochenschr; 1980 Jun 07; 110(23):916-9. PubMed ID: 7394502.
    Abstract:
    Cardiac function is regulated by four parameters: heart rate, preload, contractility and after-load. In the treatment of heart failure cardiac function is influenced by way of these parameters. The longterm pacemaker can normalize heart rate in patients with bradycardia; diuretics and volume load influence the filling pressure of the heart, while glycosides and sympathomimetic drugs increase contractility. If these mechanisms fail, peripases cardiac work. Vasodilators reduce this peripheral constriction was well as the elevated preload, and can therefore improve cardiac performance. The use and limitations of these pharmacological agents are discussed.
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