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Title: Spinal melanotic clear-cell sarcoma: a light and electron microscopic study. Author: Parker JB, Marcus PB, Martin JH. Journal: Cancer; 1980 Aug 15; 46(4):718-24. PubMed ID: 7397634. Abstract: We report a melanotic spindle-cell tumor that arose from a thoracic spinal nerve root and metastasized to both lungs. The bulk of the tumor consisted of glycogen-rich clear cells and bore a striking resemblance on light and electron microscopy to at least one variant of the clear-cell sarcoma of tendons and aponeuroses. The presence of schwannoma-like areas noted in the primary tumor on light microscopy and the formation of a highly developed basal lamina noted on ultrastructural examination suggest that the tumor may be a partially dedifferentiated malignant melanotic schwannoma. This tumor is discussed in the context of a simple histogenetic classification of melanotic tumors.[Abstract] [Full Text] [Related] [New Search]