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  • Title: Treatment of pseudohypoparathyroidism with 1 alpha-hydroxyvitamin D3.
    Author: Furukawa Y, Sohn H, Unakami H, Yumita S.
    Journal: Contrib Nephrol; 1980; 22():68-73. PubMed ID: 7398339.
    Abstract:
    A maintenance dosis of 2 microgram/day of 1 alpha-OH-D3 could keep the level of serum calcium normal in all 5 cases with pseudohypoparathyroidism, in contrast with 4.0 +/- 1.26 microgram/day needed for the 11 cases with hypoparathyroidism (8 idiopathic and 3 postoperative). The conspicuous effect of 1 alpha-OH-D3 on pseudohypoparathyroidism is likely to be attributed to the fact that the unresponsiveness of bone tissue to parathyroid hormone is corrected by the action of active vitamin D.
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