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  • Title: [Orthograde intestinal irrigation as a preoperative intestinal preparation. Reduction of the intestinal flora using antibiotics].
    Author: Huk I, Starlinger M, Schiessel R, Wewalka G, Rotter M.
    Journal: Chirurg; 1980 Feb; 51(2):106-9. PubMed ID: 7398470.
    Abstract:
    Whole gut irrigation is a now a well-established method of preoperative bowel preparation. Additional reduction of bacterial content is desirable. The influence of neomycin/bacitracin and clindamycin as well as the combination, as admixture to the whole gut irrigation, on the flora of the large intestine, was therefore investigated in a prospective controlled study. While neomycin/bacitracin caused only a reduction of aerobic, and clindamycin of the anaerobic bacteriae, the combination resulted in a nearly total eradication of detectable bacterial content at the time of operation.
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