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  • Title: [Antibiotic prophylaxis in colon surgery with Cefazolin].
    Author: Dürig M, Neff U, Rittmann WW, Leutenegger A, Oberholzer M, Wolff G.
    Journal: Helv Chir Acta; 1980 Feb; 46(5-6):721-6. PubMed ID: 7399948.
    Abstract:
    In a prospective randomized and controlled double-blind trial the effect of prophylactic systemic administration of Cefazolin in elective colorectal surgery on postoperative wound infection was investigated. The incidence of wound infection was significantly reduced (P less than 0.01) from 32% in the control group to 10% in the treated group. Furthermore there was a significant reduction (P less than 0.05) in hospital stay of about 3 days.
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