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  • Title: Alterations in glucocorticoid receptor conformation by molybdate.
    Author: Maki M, Hirose M, Chiba H.
    Journal: J Biochem; 1980 Jun; 87(6):1851-4. PubMed ID: 7400126.
    Abstract:
    Glucocorticoid receptor activities in cytosol from lactating rat mammary glands were greatly stabilized by molybdate against inactivation during incubation at 25 degrees C. The sedimentation coefficient was 9-10S in the presence of 10 mM Na2MoO4, but 6-7S in the absence of the ion. These data strongly suggest that alterations in receptor conformation induced by direct interaction with molybdate are involved in the stabilization process.
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