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  • Title: The effect of diet and fasting on gallbladder opacification during oral cholecystography in dogs as measured by computed tomography.
    Author: Fon GT, Hunter TB, Berk RN, Capp MP.
    Journal: Radiology; 1980 Sep; 136(3):585-92. PubMed ID: 7403534.
    Abstract:
    To determine the influence of diet and fasting on gallbladder opacification during oral cholecystography, 10 dogs were studied in a blind, random fashion, giving single or two consecutive doses of iopanoic acid, sodium tyropanoate, or sodium ipodate while the animals were fasting, on a normal diet, or on a low-fat diet. Gallbladder density was determined by CT to eliminate the bias created by subjective interpretation of radiographs. For maximum, first-dose gallbladder opacification during clinical cholecystography, iopanoic acid should be given with a meal and sodium ipodate while the patient is fasting; diet makes no difference with sodium tyropanoate. For maximum opacification with two consecutive doses, iopanoic acid may be given with a meal or during fasting, while sodium ipodate and sodium tyropanoate should be administered during fasting.
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