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  • Title: Protective cellular antigen of Clostridium chauvoei.
    Author: Stevenson JR, Stonger KA.
    Journal: Am J Vet Res; 1980 Apr; 41(4):650-3. PubMed ID: 7406286.
    Abstract:
    Cellular antigens of Clostridium chauvoei, strain IRP-128, were demonstrated to be important in induction of immunity against this bacterium in guinea pigs. At least one major component of the cellular antigen complex was heat-labile. Acid extraction of the bacterial cells, followed by selective purification for flagella, led to the preparation of an acid extract antigen that possessed a high degree of immunogenicity. The acid extract antigen contained flagellar components and was resolved into two major and approximately five minor protein components by polyacrylamide-gel electrophoresis.
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