These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Heterogeneous distribution of the sodium-dependent alanine transport activity in the rat hepatocyte plasma membrane.
    Author: van Amelsvoort JM, Sips HJ, Apitule ME, van Dam K.
    Journal: Biochim Biophys Acta; 1980 Aug 14; 600(3):950-60. PubMed ID: 7407153.
    Abstract:
    The localization of the sodium-dependent alanine uptake activity in rat liver cells was studied. Fractions representative of the canalicular, the contiguous (lateral) and the blood-sinusoidal surface of the hepatocyte were isolated by means of centrifugal fractionation and density gradient centrifugation. The distribution of various marker-enzyme activities in conjunction with the occurrence of alanine transport activity was studied both in fractions obtained after zonal density gradient centrifugation, and in the subcellular fractions mentioned above. It is concluded that the sodium-dependent alanine transport activity is primarily located in the blood-sinusoidal plasma membrane of the hepatocyte.
    [Abstract] [Full Text] [Related] [New Search]