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  • Title: Evidence for independent regulation of dolichol and cholesterol synthesis in developing mouse brain.
    Author: James MJ, Kandutsch AA.
    Journal: Biochim Biophys Acta; 1980 Aug 11; 619(2):432-5. PubMed ID: 7407226.
    Abstract:
    In order to investigate the regulatory inter-relationships between the branching pathways of dolichol and cholesterol synthesis, we have measured the changing rates of synthesis for these two lipids in developing mouse brains. A sharp peak in the rate of dolichol synthesis occured at 3-7 days after birth which did not coincide with changes in cholesterol synthesis, suggesting independent regulation of dolichol and cholesterol synthesis in developing mouse brains.
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