These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Enhancement of sprouting and putative regeneration of central noradrenergic fibers by morphine.
    Author: Harston CT, Morrow A, Kostrzewa RM.
    Journal: Brain Res Bull; 1980; 5(4):421-4. PubMed ID: 7407638.
    Abstract:
    Treatment of newborn rats with 6-hydroxydopa (6-OHDOPA, 60 micrograms/g IP) increased the levels of norepinephrine in the adult cerebellum and hindbrain. Concurrent treatment with morphine sulfate (20 micrograms/g IP) potentiated the response to 6-OHDOPA in the cerebellum and pons-medulla. In addition, increased noradrenergic neurite density in 4 week cerebellar cortex (as observed with histofluorescent staining by glyoxylic acid) suggests that neonatal morphine increased the sprouting of noradrenergic neurons in the 6-OHDOPA treated rats.
    [Abstract] [Full Text] [Related] [New Search]