These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Clinical evaluation of antiarrhythmic effects of disopyramide by multiclinical controlled double-blind methods.
    Author: Kimura E, Mashima S, Tanaka T.
    Journal: Int J Clin Pharmacol Ther Toxicol; 1980; 18(8):338-43. PubMed ID: 7409935.
    Abstract:
    Used orally, in double-blind cross-over controlled trials conducted on 73 patients, disopyramide, a newly developed antiarrhythmic agent, was found to be more effective than an inert placebo (lactose), with a statistically significant difference, and to be as effective as quinidine sulfate in suppressing ventricular and supraventricular premature beats. In double-blind studies with 42 patients, it was also found to be as effective as quinidine sulfate in preventing the recurrence of atrial fibrillation after successful cardioversion. In non-blind studies attacks of paroxysmal supraventricular and ventricular tachycardia and transient atrial fibrillation were effectively prevented in the respective arrhythmias in more than 70% of the cases.
    [Abstract] [Full Text] [Related] [New Search]