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  • Title: [Experimental study of the anatomical-physiological basis for pulmonary circulation shunting in extensive lung resections].
    Author: Vaĭda RI.
    Journal: Vestn Khir Im I I Grek; 1980 Jun; 124(6):9-14. PubMed ID: 7414871.
    Abstract:
    Bilateral extensive resections of lungs resulted in the development of stable pulmonary arterial hypertension, its degree correlating with the duration of the postoperative observation. Continuous hypertension in the pulmonary artery system is responsible for destructive changes in the intrapulmonary vessels and lung parenchyma promoting elevation of the vascular resistance in the small circuit and increased load to the right ventricle which further leads to decompensation of the cardio-pulmonary system. The author has shown that creation of extrapulmonary arterio-venous anastomosis in major lung resections can prevent the overloading of the right ventricle in the postoperative period, makes better conditions for compensatory changes in the remaining lung tissue without developing fibrosis.
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