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  • Title: Methyl red azo-reductase and its induction by 3-methylcholanthrene in the liver by different species.
    Author: Renton KW.
    Journal: Xenobiotica; 1980 Apr; 10(4):243-6. PubMed ID: 7415204.
    Abstract:
    1. Methyl red azo-reductase activity in the liver cytosol of mouse and sheep was considerably less than in the rat, guinea-pig, rabbit and hamster. In the mouse, the total activity of this soluble enzyme to reduce methyl red was only 4% of that found in rat. 2. Species variation in methyl red azo-reductase of microsomes was relatively small compared to that of the cytosol. 3. Azo-reductase in the cytosol of mouse liver also differed from that of the rat in its resistance to the inductive effects of 3-methylcholanthrene.
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